As a traditional artist I'd say yes, but it depends on the technique, the most evident example is oilpainting where you can infinitely layer your work and so like that triggering chemical reactions in the paint that make the colors brighter or more muted, darker blacks etc, this can be done with many different oils and specific " mixes" between solvents and products, the quantities must be very specific thoug, or you could just go in the most agressive way which is layering paint using just turpenoid.
Hope you find it useful, if you are interested in such things just ask