What are you using? Photoshop? If so, definitely take advantage of the smoothing slider. I knock it up to anywhere from 12-25% depending how long and precise the line needs to be.
Unfortunately with digital it's not all about dexterity; with any software/tablet there's the annoying "wiggle". Procreate in particular has not yet addressed this; their style of smoothing doesn't work for long strokes which need to be drawn slowly for precision.
I highly recommend the free app Krita, actually. It was absolutely wonderful to draw and paint in, and pretty intuitive to get started. It has one of the best smoothing functions out there. On tablets, Infinite Painter has good smoothing.
Finally, it's not that perfect lines have to be the goal — there are beautiful drawing styles with messy/wild lines! Even for straight and modern architecture like this. I can try to find some examples if you'd like.
P.S. Do tell me if I'm just going on about things you already know and not addressing the specifics you do have questions about!