Why is Cthulu spawning from her chest!?
This looks interesting though! One thing that seems off is the color. Skin is rarely gray like that, and you seem to have a lot of it, making it seem muddy or dirty. What skin is really like, is nicely show on your arm. It has a darker side, with a heavily saturated midtones and then a lighter side. Light usually kills off the saturation, and you could push that further. Her face looks warped, and it is true that her right eye is supposed to be smaller when her head is to the side like that, that eye is a bit too small as it is right now.
As for the skulls, they aren't very anatomically correct, but they're just assets! As for flesh; it looks kind of off, but I haven't ever tried to render that, so I can't really put my finger on what is off. Anyway, nice seeing you post! Really loved your "Whats lives above the clouds ?", it is mysterious, interesting and it tells a very cool story with some nice composition Keep up the good work!